The Astros enter as favorites with odds of -145 against the White Sox's +125. Houston won five of seven regular-season matchups against Chicago, including three of the last four. sport-newz.biz
The White Sox had at least 100 losses in each of the last three seasons before this year, while the Astros finished 81-81 but still won the AL West despite having a negative run differential of -32 runs.
